Major highways and roads across Colorado are being shut down as the bomb cyclone wreaks havoc, triggering innumerable accidents, leaving people stranded in cars and tripping up traffic lights.

The Colorado Department of Transportation has shut down Interstate 70, one of the nation’s busiest east-west conduits, in both directions from Tower Road in Aurora to the Kansas state line as the massive storm pounds the state.

The storm triggered more than 100 accidents, making many Colorado roads and highways nearly impenetrable. Two people have been seriously injured in weather-related crashes including a Colorado State Patrol trooper and a Denver pedestrian.

In Denver alone, 110 crashes were reported as of 3:10 p.m. Colorado Springs police and El Paso County sheriff deputies were attempting to reach about 500 stranded drivers in the city and county.

“That’s dangerous for people who are out on the road and drivers who are trying to navigate dangerous roads … (They are) impeding snowplows, emergency vehicles and law enforcement,” according to a 3:12 p.m. Colorado Springs police tweet.

In addition to an indefinite I-70 closure:

  •  Interstate 25 is closed from Wellington to the Wyoming State line.
  • I-70 is closed in both directions at Vail Pass.
  • All lanes of northbound I-25 are closed at County Line Road, according to the Colorado Department of Transportation.
  • U.S. Highway 285 is closed between Fairplay and the top of Kenosha Pass because of zero visibility, blowing and drifting snow and blizzard conditions, according to the Colorado State Patrol.
  • The right lanes of westbound U.S. 36 closed between Church Ranch Road and Colorado 128, according to CDOT. The eastbound express lane of U.S. 36 between Colorado 170 and West Flatiron Crossing Drive is closed following a 7 a.m. crash.
  • Interstate 76 is closed in both directions from U.S. 85 to the Nevada border.
  • Southbound I-25 is closed from Castle Rock to Monument Hill. Northbound lanes of I-25 are closed from Castle Rock to Colorado Springs.
  • Both directions of I-25 are closed from Woodman Road to Meadows Parkway.
  • Westbound I-70 is closed from Golden to Idaho Springs.
  • A jack-knifed semi-tractor trailer closed Highway 85 at Manhart.
  • The right lane of westbound C-470 is closed at West Alameda Parkway due to a jackknifed semi-tractor trailer.
  • Colorado 58 is closed in both directions from Wheat Ridge to Golden.

A CSP trooper was injured in a Wednesday morning crash on I-76 at mile marker 47, according to a CSP tweet.

Traffic lights are going out across the Denver metro including in Broomfield, including in the Interlocken and FlatIron area and along West 120th Avenue.

Brighton Fire Department is scrambling from one accident to the next. Firefighters are picking up stranded motorists.

The storm is impacting RTD and commercial bus services as well.

In Wheat Ridge, the G-Line is malfunctioning at Independence, Miller, and Oaks streets. The streets are closed, according to Wheat Ridge Police bulletin.

All bus rides to and from Denver on Ride Bustang have been canceled as of 12:30 p.m. “It is no longer safe to operate.”

Many police departments across the state have sent out blizzard survival tips, urging people to carry emergency kits with them if they venture out into the formidable weather.

The Colorado Department of Transportation also has issued travel alerts linked to avalanche mitigation work and is warning of long delays at U.S. 160 on Wolf Creek Pass, beginning at 6 a.m.; and U.S. 550 on Coal Bank Pass and Molas Pass starting at 7 a.m.